Intravitreal Injection

What is an intravitreal injection?

In this procedure, a small amount of medication is injected into the eye under local anesthesia. The medications used include ranibizumab, aflibercept, bevacizumab, or triamcinolone.

These injections are performed for swelling of the central part of the retina (macular edema) or the growth of new blood vessels on the retina. The medication has a temporary effect and must therefore be administered regularly.

Ranibizumab and aflibercept are specifically developed for use in the eye and are subject to strict reimbursement rules. Bevacizumab is marketed as a chemotherapy drug and is used off-label in the eye worldwide. This means that the manufacturer has not conducted studies on the efficacy of bevacizumab in the eye and has not registered the product for ocular use. Ophthalmologists rely on extensive international scientific research and years of experience to use bevacizumab in the eye.

Triamcinolone is marketed for surgical use but, like bevacizumab, is also used off-label by ophthalmologists for intravitreal injections. Bevacizumab and triamcinolone are not reimbursed by health insurance.

What preparation should I do?
How is the injection carried out?
What happens after the treatment?
Possible Complications

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